High Levels Psa Blood Test has been detected in various tissues of the male urogenital system but only prostate glandular cells and endothelial cells secrete it. The PSA level in the serum of healthy men is between 0.1 ng/mL and 2.6 ng/mL. It can be elevated in malignant conditions such as prostate cancer, and in benign conditions such as benign prostatic hyperplasia and prostatitis. A PSA level of 4 to 10 ng/mL is considered to be in the "gray‐zone" and above 10 ng/mL is highly indicative of cancer.3 Patients with PSA values between 4‐10 ng/mL should undergo further analysis of the prostate by biopsy. Authorities have begun to explore the possibility of using PSA levels lower than 4.0 ng/mL as the upper limit of normal for screening examinations. By lowering the PSA cutoff from 4 to 3 ng/mL, an increase in cancer detection by 13.2% can be achieved
|
Product name |
PSA Rapid Test Device |
|
Item type |
PSA-W21-2 |
|
Specimens |
Whole blood/Plasma/Serum |
|
Shelf life |
2 years |
|
Test Time |
Waiting about 15 minutes |
|
Certificate |
CE, ISO:13485 |
|
OEM |
Acceptable |
|
Storage condition |
The kit should be stored at 2-30°C |
BIBLIOGRAPHY
1. Wang MC, Valenzuela LA, Murphy GP, et al., Purification of human prostate specificity antigen. Invest Urol 1979; 17: 159‐163.
2. Christens A, Laurell CB, Lilja H. Enzymatic activity of prostate –specific antigen and its reaction with extracellular serine proteinase Inhibitors. Eur J Biochem 1990; 194:755‐763.
3. Catalona WJ, Southurick PC, Slawin KM, et al., Comparison of percent free PSA, PSA density and age-specific PSA cut-offs for prostate cancer detection and staging. Urology 2000 Aug 1:56(2):255‐60.
4. Lodding P, Aus G, Bergdahl S, et al. Characteristics of screening detected prostate cancer in men 50 to 66 years old with 3 to 4 ng./mL. prostate specific antigen. Journal of Urology 159(3): 899‐903, 1998.
MATERIALS
Materials Provided
|
Tests |
Droppers |
|
Buffer |
Package insert |
Materials Required But Not Provided
|
Specimen collection containers |
Lancets (for fingerstick whole blood only) |
|
Centrifuge |
Timer |
|
Positive control |
Negative control |
|
Heparinized capillary tubes and dispensing bulb (for fingerstick whole blood only) |
|
QUALITY CONTROL
A procedural control is included in the test. A colored line appearing in the control line region (C) is considered an internal procedural control. It confirms sufficient specimen volume, adequate membrane wicking and correct procedural technique.
Control standards are not supplied with this kit; however, it is recommended that positive and negative controls be tested as a good laboratory practice to confirm the test procedure and to verify proper test performance.
FAQ
Q: What is considered a high PSA level?
A: In general, a PSA level above 4.0 ng/mL is considered abnormal and may result in a recommendation for prostate biopsy. However, because PSA levels increase with age, some doctors apply a higher cutoff (such as 5 ng/ml) for older men and a lower cutoff ( such as 2.5 ng/mL) for younger men
Q: What to worry if your PSA level is high?
A: If you had a PSA test for a prostate cancer screening or because you have prostate symptoms: High PSA levels can mean you have prostate cancer or a prostate condition that's not cancer, such as an infection (causing prostatitis) or an enlarged prostate.
Q: Can PSA be very high without cancer?
A: In fact, for individuals with high levels of PSA, only 2% will have a form of prostate cancer requiring medical intervention. Some of the common causes for elevated PSA include age, prostatitis, benign prostatic hyperplasia, and urinary tract infections.
Q: What is the normal size of the prostate at the age of 70?
A:
Prostate Size Chart By Age
| Age Range | Typical Prostate Size | Classification |
|---|---|---|
| 20-40 | 20-30 cc | Normal |
| 40-60 | 30-50 cc | Mildly Enlarged |
| 60+ | 50-80 cc | Moderately Enlarged |
| 70+ | 80+ cc | Severely Enlarged |
Q: What will an urologist do for high PSA?
A: Your urologist will discuss your individual situation with you. If the MRI scan is equivocal (neither low or high risk) and the PSA is high for the size of your prostate, or there are other reasons to suspect prostate cancer, you are likely to be offered a biopsy.
Q: Can high PSA be cured?
A: The higher your PSA levels are, the more likely it is that you have active prostate cancer. Some scientific research has found that it's possible to lower your PSA numbers and reduce risk of developing or returning cancer by making lifestyle changes, like eating certain foods and being more physically active.
Hot Tags: high levels psa blood test, China high levels psa blood test manufacturers, suppliers, factory, Psa Semi Quantitative Rapid Test, psa rapid test, Psa Rapid Test Kit
